DIAGNOSIS OF INFECTIONS CAUSED BY UREAPLASMA UREALYTICUM AND MYCOPLASMA HOMINIS

Abstract

Objectives: The study aimed to determine the incidence of infections caused by M. hominis and U. urealyticum at the University Hospital of  Split from 1.1.2020 to 31.12.2020 and to determine the susceptibility of these isolates to antibiotics in the same period. 

Materials and methods: The study was carried out on data on patients with isolated M. hominis or U. urealyticum during this period. The data were collected from the Department of Microbiology and Parasitology, University Hospital of Split (UHS). As a diagnostic method, the commercial cultivation set MYCOFAST RevolutioN was used, divided into two phases of the test.

Results: Department of Microbiology and Parasitology UHS received 638 samples suspected of infection with ureaplasma and mycoplasma. Of these samples, in 7% (45 samples) U. urealyticum and 0.5% (3 samples) for M. hominis were proven. Ureaplasma was predominantly isolated from the genital system in women of generative age. The majority of tested strains were susceptible to doxycycline (94,4 %), erythromycin (82,9 %), moxifloxacin (80,5 %), levofloxacin (77,8 %) and tigecycline (76 %); and resistant to clindamycin (95,8 %). However, the sample size for mycoplasma was too small for statistical analysis.

Conclusion: The results of this research indicate the highest incidence of urogenital mycoplasmas in women of reproductive age, which emphasizes the importance of early diagnosis and treatment, in order to prevent complications of pregnancy and the postpartum period. Although most isolates are sensitive to macrolides, constant surveillance and antibiotic susceptibility testing is required, due to increasing and growing resistance worldwide.